Feb 3 2010

Statin Side Effect

When it comes to treating high cholesterol, you are often prescribed certain drugs by your doctors. These are called statin drugs. The statins are a specific class of drugs, which are more formally referred to as pharmaceuticals, and are used to reduce cholesterol levels.

How does statins work …………….
Statins block production of cholesterol in the body by inhibiting the enzyme HMG-CoA reductase in the early stages of their synthesis in the mevalonate pathway. Cholesterol is one of the three finished in the mevalonate chain. The same pathway also provide the co-enzyme Q10, or Co-Q10, and dilochol. It is an unfortunate consequence of statin inhibition of both unexpected and Co-Q10 synthesis dilochol.

This explains that statin lowers coenzyme Q10. Coenzyme Q10 is an essential nutrient made in the cell mitochondria , to produce energy for the cell. Mitochondria use to produce carbohydrat, oxygen and energy known as ATP molecules. Without ATP, cells could do anything. The damaged tissue could not be repaired. The cells do not divide or produce or use, proteins, enzymes or hormones.

Heart requires high levels of oxygen, sugar and Co-Q10, because it uses lots of energy. A form of co-Q10 called ubiquinone is present in all cell membranes, where it plays a role in maintaining the integrity of this membrane, so critical to nerve conduction and muscle contraction. Co-Q10 is also important for the formation of elastin and collagen in the connective tissue of the skin, making the muscles and cardiovascular system.

Side effect of statin ……
There are many accusations that are made against the use of statin drug dangers and some of these dangers include: peripheral neuropathy, muscle damage, elevated liver enzyme indices, plasma fibrinogen levels and including kidney damage.
But the most commons side effect is muscle pain and weakness. Noted In fact, many patients who start on statins, almost immediately, general fatigue and weakness. This is due to the depletion of Co-Q10 is needed to support muscle function. The pharmaceutical industry insists that only 2-3% of patients, muscle aches and cramps, get when, in fact, noted in a study by Golomb ® that 98% of patients taking Lipitor and one third of patients Mevacor ® (with a low dose of statin) suffered a tangible way of significant muscle problems.

Some people who take statins lose coordination of their muscles. Some develop pain in the muscles, some are not able to write to the loss of fine motor skills. Many lose their strength and movement. Others fall more often than their muscles refuse any trouble sleeping because of muscle spasms and convulsions. Worse still, many people with most of these side effects. The problems are so numerous that it is difficult to list everyone could experience symptoms. These problems are not the “disease” comes from high cholesterol, but the disease of ignorance to the prescription of these drugs.

As we age, levels of co-Q10 decrease naturally. From age 20 to 80, Co-Q10 decrease of almost 50%. In addition to the natural decline of the Co-Q10 is a natural decline in energy and an increased risk of heart disease, stroke and cancer. If the natural decline of the Co-Q10 levels increase the risk of fatigue, cancer, heart disease and stroke, it is not logical that the acceleration would decrease the levels of Co-Q10 with statin drugs, the same effect? They have indeed!

Demonstrate the importance of Co-Q10 Cardiovascular Health, in a randomized, double-blind, placebo-controlled cons, making people either taking or not taking statins, supplementation with Co-Q10 reduces the risk of heart attack and death in patients with heart disease and stroke by 50%, regardless of whether they were on a statin or not.

In addition, the Co-Q10 has been shown that blood levels of vitamin E to increase significantly and increase the level of protective HDL. As low HDL is a major risk factor for heart disease, there is always an advantage. Statins have been shown no benefit in addition to the supplement offer Co-Q10. Let me be clear – in this study, only the co-enzyme Q10 provided an advantage, not drugs!.
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